In 1962, the Giants lost a seven-game Series to the Yankees, which ended on Willie McCovey's liner to Yankees second baseman Bobby Richardson with two runners in scoring position.
The Yankees won 1-0.
Several Giants from that '62 team will be at the ballpark, including the manager, Alvin Dark, along with Willie Mays and McCovey, more than 14 in all.
The Giants also lost the World Series in 2002 (talk about anniversaries) and 1989 and won it all in 2010. Two years later, they're trying to return to championship form.
They lost four of their first five games this season, so Thursday's 4-2 victory in Colorado provides some momentum heading into the home opener. Matt Cain, who has pitched once since signing his $112.5 million extension, will start Friday.
Before Thursday, the only Giants starter who did well was Barry Zito, who threw a shutout Tuesday. On Thursday, Madison Bumgarner pitched into the eighth inning for his first win and got support from Melky Cabrera, who hit an RBI single in the fourth and an RBI double in the sixth.