Sanchez was hitting as a DH but not playing second base. Manager Bruce Bochy said Sanchez was "hesitant" with his throws, a sign he's not close to 100 percent.
He might not be for a while.
"Obviously, I'm going to have ups and downs probably all year," Sanchez said. "There will be tightness in there. There will be soreness. But that's all part of the process."
The Giants already spoke with shortstop Brandon Crawford to take cutoffs in right-center to lessen the load for Sanchez.
As for Posey, he was hitless in his first seven at-bats until getting his first hit, a home run off Cleveland lefty Tony Sipp. Posey worked his way up to catching four innings on Thursday.
"I still think it's about getting ready and preparation and getting at-bats and seeing pitches and trying to work on timing," Posey said. "I'm just glad I hit it hard. That's the goal coming up every time, just to hit it hard."
As for Wilson, both of his first two outings were impressive, a good sign after he was shut down late last season with a bum elbow and spent most of the offseason rehabbing.
"The last two performances, I can say it has been worth the wait," Wilson said.